Thromboangiitis obliterans.

نویسندگان

  • Gregory Piazza
  • Mark A Creager
چکیده

Case presentation: A 39-year-old male smoker with a 2-year history of calf discomfort on ambulation culminating in left femoral-to-peroneal artery bypass presented with right leg discomfort and recurrent painful subcutaneous nodules on his feet and calves. Biopsy of a nodule from his right foot was interpreted as vasculitis with thrombosis and fibrinoid necrosis in subcutaneous vessels, and the patient was prescribed immunosuppressive therapy with prednisone and azathioprine. His symptoms progressed, and the patient referred himself to the vascular medicine clinic for a second opinion. On examination, the patient had tender erythematous nodules on his right foot and calf following the course of the right lesser saphenous vein consistent with extensive superficial thrombophlebitis. The right femoral, popliteal, and pedal pulses were palpable. The left femoral-to-peroneal graft and left pedal pulses were also palpable. Ankle:brachial indices were normal in each leg. The constellation of arterial occlusive disease and superficial thrombophlebitis in a young smoker was most consistent with thromboangiitis obliterans.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Molecular mechanisms regulating immune responses in thromboangiitis obliterans: a comprehensive review

Thromboangiitis obliterans (TAO) is a thrombotic-occlusive as well as an inflammatory peripheral vascular disease with unknown etiology. Recent evidence has supported the immunopathogenesis of the disease, however, the factors contributing to the altered immune function and vascular tissue inflammation are still unclear. This review was intended to collate the more current knowledge on the regu...

متن کامل

The Incidence and Prevalence of Thromboangiitis Obliterans in Taiwan: A Nationwide, Population-based Analysis of Data Collected from 2002 to 2011

OBJECTIVE To estimate the incidence and prevalence of thromboangiitis obliterans in Taiwan in the period spanning from 2002 to 2011. METHODS We identified all incident and prevalent cases with a diagnosis of thromboangiitis obliterans (International Classification of Diseases, Ninth Revision code 443.1) in the period spanning from 2002 to 2011 using Taiwan's National Health Insurance Research...

متن کامل

Recurrent Vitreous Haemorrhage Associated with Thromboangiitis Obliterans.

THROMBOANGIITIS obliterans has been considered to be a disease of the blood vessels which usually affects the vessels of the limbs. It has been established, however, that it can affect any of the blood vessels in the body, including those which supply the brain and the retina. This is the report of a case which presented with vitreous haemorrhage, and in which the diagnosis of thromboangiitis o...

متن کامل

End stage renal disease caused by thromboangiitis obliterans: a case report

INTRODUCTION Thromboangiitis obliterans or Buerger's disease is a nonatherosclerotic, segmental, inflammatory vasculitis that is strongly associated with tobacco products and commonly affects the small- and medium-sized arteries of the upper and lower extremities. However, the disease can, rarely, involve large central or visceral arteries. We report here the case of end stage renal disease due...

متن کامل

Thromboangiitis obliterans (Buerger's disease)

Thromboangiitis Obliterans is a non-atherosclerotic inflammatory disease of unknown etiology, which has a strong association with tobacco. We present current concepts on the pathophysiology and diagnosis, as well as a review in treatments.

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Circulation

دوره 121 16  شماره 

صفحات  -

تاریخ انتشار 2010